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Downregulation of Rab27A contributes to metformin-induced suppression of breast cancer stem cells

Cancer stem cells (CSCs) are associated with tumor initiation, therapeutic resistance, relapse and metastasis. However, the underlying mechanisms CSCs use to preserve stemness are not yet fully understood. The present study demonstrated that the expression of RAB27A, member RAS oncogene family (Rab2...

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Bibliografische gegevens
Gepubliceerd in:Oncol Lett
Hoofdauteurs: Feng, Feixue, Zhang, Jianping, Fan, Xiaoxuan, Yuan, Fang, Jiang, Yinghao, Lv, Ruihua, Ma, Yanxia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588170/
https://ncbi.nlm.nih.gov/pubmed/28928832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6542
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