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Downregulation of Rab27A contributes to metformin-induced suppression of breast cancer stem cells

Cancer stem cells (CSCs) are associated with tumor initiation, therapeutic resistance, relapse and metastasis. However, the underlying mechanisms CSCs use to preserve stemness are not yet fully understood. The present study demonstrated that the expression of RAB27A, member RAS oncogene family (Rab2...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncol Lett
Auteurs principaux: Feng, Feixue, Zhang, Jianping, Fan, Xiaoxuan, Yuan, Fang, Jiang, Yinghao, Lv, Ruihua, Ma, Yanxia
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588170/
https://ncbi.nlm.nih.gov/pubmed/28928832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6542
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