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Dichloroacetate induces protective autophagy in esophageal squamous carcinoma cells

Dichloroacetate (DCA) is an inhibitor of pyruvate dehydrogenase kinase, which promotes the flux of carbohydrates into mitochondria and enhances the aerobic oxidation of glucose. DCA has previously been demonstrated to exhibit antitumor properties. The present study revealed that treatment with DCA i...

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Bibliographic Details
Published in:Oncol Lett
Main Authors: Jia, Hong-Yu, Wang, He-Nan, Xia, Feng-Yu, Sun, Yan, Liu, Hong-Li, Yan, Li-Li, Li, Shan-Shan, Jiang, Dong-Chun, Xu, Mei-Mei
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588168/
https://ncbi.nlm.nih.gov/pubmed/28928817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6562
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