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MEK inhibitor enhances sensitivity to chemotherapeutic drugs in multidrug resistant hepatocellular carcinoma cells

The aim of the present study was to investigate the association between the mitogen-activated protein kinase (MAPK) signal transduction pathway and multidrug resistance in hepatocellular carcinoma cells. A Cell Counting Kit-8 assay was used to determine the drug sensitivity of HepG2 and HepG2/ADM he...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncol Lett
Hauptverfasser: Meng, Qingliang, He, Xiaoqi, Xie, Guangwei, Tian, Qingzhong, Shu, Xiaogang, Li, Jin, Xiao, Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588134/
https://ncbi.nlm.nih.gov/pubmed/28928846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6494
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