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Oxygen-Dependent Lipid Profiles of Three-Dimensional Cultured Human Chondrocytes Revealed by MALDI-MSI

[Image: see text] Articular cartilage is exposed to a gradient of oxygen levels ranging from 5% at the surface to 1% in the deepest layers. While most cartilage research is performed in supraphysiological oxygen levels (19–21%), culturing chondrocytes under hypoxic oxygen levels (≤8%) promotes the c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Anal Chem
Hauptverfasser: Bakker, Brenda, Eijkel, Gert B., Heeren, Ron M. A., Karperien, Marcel, Post, Janine N., Cillero-Pastor, Berta
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2017
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588094/
https://ncbi.nlm.nih.gov/pubmed/28727417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b02265
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