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Highly Improved Electrospray Ionization-Mass Spectrometry Detection of G-Quadruplex-Folded Oligonucleotides and Their Complexes with Small Molecules
[Image: see text] G-quadruplexes are nucleic acids structures stabilized by physiological concentration of potassium ions. Because low stability G-quadruplexes are hardly detectable by mass spectrometry, we optimized solvent conditions: isopropanol in a triethylamine/hexafluoroisopropanol mixture hi...
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| Izdano u: | Anal Chem |
|---|---|
| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American
Chemical
Society
2017
|
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5588092/ https://ncbi.nlm.nih.gov/pubmed/28787153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b01282 |
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