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Highly Improved Electrospray Ionization-Mass Spectrometry Detection of G-Quadruplex-Folded Oligonucleotides and Their Complexes with Small Molecules

[Image: see text] G-quadruplexes are nucleic acids structures stabilized by physiological concentration of potassium ions. Because low stability G-quadruplexes are hardly detectable by mass spectrometry, we optimized solvent conditions: isopropanol in a triethylamine/hexafluoroisopropanol mixture hi...

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Detaylı Bibliyografya
Yayımlandı:Anal Chem
Asıl Yazarlar: Scalabrin, Matteo, Palumbo, Manlio, Richter, Sara N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2017
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588092/
https://ncbi.nlm.nih.gov/pubmed/28787153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b01282
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