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Resistance to the mTOR inhibitor everolimus is reversed by the downregulation of survivin in breast cancer cells

Everolimus (RAD001) is an inhibitor of mammalian target of rapamycin used in combination with exemestane to treat hormone receptor-positive advanced breast cancer. However, not all patients are equally sensitive to RAD001 and certain patients develop resistance. Therefore, the present study analyzed...

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Dades bibliogràfiques
Publicat a:Oncol Lett
Autors principals: Taglieri, Ludovica, De Iuliis, Francesca, Giuffrida, Anna, Giantulli, Sabrina, Silvestri, Ida, Scarpa, Susanna
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587981/
https://ncbi.nlm.nih.gov/pubmed/28927154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6597
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