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Resistance to the mTOR inhibitor everolimus is reversed by the downregulation of survivin in breast cancer cells

Everolimus (RAD001) is an inhibitor of mammalian target of rapamycin used in combination with exemestane to treat hormone receptor-positive advanced breast cancer. However, not all patients are equally sensitive to RAD001 and certain patients develop resistance. Therefore, the present study analyzed...

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Bibliografiske detaljer
Udgivet i:Oncol Lett
Main Authors: Taglieri, Ludovica, De Iuliis, Francesca, Giuffrida, Anna, Giantulli, Sabrina, Silvestri, Ida, Scarpa, Susanna
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587981/
https://ncbi.nlm.nih.gov/pubmed/28927154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6597
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