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FANCJ helicase controls the balance between short- and long-tract gene conversions between sister chromatids

The FANCJ DNA helicase is linked to hereditary breast and ovarian cancers as well as bone marrow failure disorder Fanconi anemia (FA). Although FANCJ has been implicated in the repair of DNA double-strand breaks (DSBs) by homologous recombination (HR), the molecular mechanism underlying the tumor su...

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Publicat a:Nucleic Acids Res
Autors principals: Nath, Sarmi, Somyajit, Kumar, Mishra, Anup, Scully, Ralph, Nagaraju, Ganesh
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587752/
https://ncbi.nlm.nih.gov/pubmed/28911102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx586
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