Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model

Pericytes represent important support cells surrounding microvessels found in solid organs. Emerging evidence points to their involvement in tumor progression and metastasis. Although reported to be present in the human lung, their specific presence and functional orientation within the tumor microe...

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Publicado en:Sci Rep
Main Authors: Bichsel, Colette A., Wang, Limei, Froment, Laurène, Berezowska, Sabina, Müller, Stefan, Dorn, Patrick, Marti, Thomas M., Peng, Ren-Wang, Geiser, Thomas, Schmid, Ralph A., Guenat, Olivier T., Hall, Sean R. R.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587684/
https://ncbi.nlm.nih.gov/pubmed/28878242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09928-1
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