Avelumab in patients with chemotherapy-refractory metastatic Merkel cell carcinoma: a multicentre, single-group, open-label, phase 2 trial

BACKGROUND: Merkel cell carcinoma is a rare, aggressive skin cancer with poor prognosis in patients with advanced disease. Current standard care uses various cytotoxic chemotherapy regimens, but responses are seldom durable. Tumour oncogenesis is linked to Merkel cell polyomavirus integration and ul...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Lancet Oncol
Egile Nagusiak: Kaufman, Howard L, Russell, Jeffery, Hamid, Omid, Bhatia, Shailender, Terheyden, Patrick, D’Angelo, Sandra P, Shih, Kent C, Lebbé, Céleste, Linette, Gerald P, Milella, Michele, Brownell, Isaac, Lewis, Karl D, Lorch, Jochen H, Chin, Kevin, Mahnke, Lisa, von Heydebreck, Anja, Cuillerot, Jean-Marie, Nghiem, Paul
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587154/
https://ncbi.nlm.nih.gov/pubmed/27592805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(16)30364-3
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