Long-Term Dose-Dependent Agalsidase Effects on Kidney Histology in Fabry Disease

BACKGROUND AND OBJECTIVES: Dose-dependent clearing of podocyte globotriaosylceramide has previously been shown in patients with classic Fabry disease treated with enzyme replacement. Our study evaluates the dose-dependent effects of agalsidase therapy in serial kidney biopsies of patients treated fo...

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Pubblicato in:Clin J Am Soc Nephrol
Autori principali: Skrunes, Rannveig, Tøndel, Camilla, Leh, Sabine, Larsen, Kristin Kampevold, Houge, Gunnar, Davidsen, Einar Skulstad, Hollak, Carla, van Kuilenburg, André B.P., Vaz, Frédéric M., Svarstad, Einar
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2017
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586567/
https://ncbi.nlm.nih.gov/pubmed/28625968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.01820217
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