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Sustained Activation of ERK1/2 MAPK in Schwann Cells Causes Corneal Neurofibroma

Recent studies have shown that constitutive activation of extracellular signal-regulated kinases 1 and 2 (ERK1/2) in Schwann cells (SCs) increases myelin thickness in transgenic mice. In this secondary analysis, we report that these transgenic mice develop a postnatal corneal neurofibroma with loss...

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Detalhes bibliográficos
Publicado no:J Neurosci Res
Main Authors: Bargagna-Mohan, Paola, Ishii, Akihiro, Lei, Ling, Sheehy, Daniel, Pandit, Saagar, Chan, Grace, Bansal, Rashmi, Mohan, Royce
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586542/
https://ncbi.nlm.nih.gov/pubmed/28489286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.24067
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