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A Model for Epigenetic Inhibition via Transvection in the Mouse

Transvection is broadly defined as the ability of one locus to affect its homologous locus in trans. Although it was first discovered in the 1950s, there are only two known cases in mammals. Here, we report another instance of mammalian transvection induced by the Cre/LoxP system, which is widely us...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Rodriguez, Juan D., Myrick, Dexter A., Falciatori, Ilaria, Christopher, Michael A., Lee, Teresa W., Hannon, Gregory J., Katz, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586367/
https://ncbi.nlm.nih.gov/pubmed/28696215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.201913
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