Albumin Removal from Human Serum using Surface Nanopockets on Silica-coated Magnetic Nanoparticles

Selective removal of albumin from human serum is an essential step prior to proteomic analyses, especially when using mass spectrometry. Here we report stable synthetic nanopockets on magnetic nanoparticle surfaces that bind to human serum albumin (HSA) with high affinity and specificity. The nanopo...

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Publicado en:Chem Commun (Camb)
Autores principales: Bhakta, Snehasis, Dixit, Chandra K., Bist, Itti, Macharia, John, Shen, Min, Kadimisetty, Karteek, He, Junkai, Dutta, Biswanath, Suib, Steven L., Rusling, James F.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586046/
https://ncbi.nlm.nih.gov/pubmed/28770934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc03412a
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