Albumin Removal from Human Serum using Surface Nanopockets on Silica-coated Magnetic Nanoparticles

Selective removal of albumin from human serum is an essential step prior to proteomic analyses, especially when using mass spectrometry. Here we report stable synthetic nanopockets on magnetic nanoparticle surfaces that bind to human serum albumin (HSA) with high affinity and specificity. The nanopo...

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Détails bibliographiques
Publié dans:Chem Commun (Camb)
Auteurs principaux: Bhakta, Snehasis, Dixit, Chandra K., Bist, Itti, Macharia, John, Shen, Min, Kadimisetty, Karteek, He, Junkai, Dutta, Biswanath, Suib, Steven L., Rusling, James F.
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586046/
https://ncbi.nlm.nih.gov/pubmed/28770934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc03412a
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