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Cell Spheroids with Enhanced Aggressiveness to Mimic Human Liver Cancer In Vitro and In Vivo

We fabricated a spheroid-forming unit (SFU) for efficient and economic production of cell spheroids. We optimized the protocol for generating large and homogenous liver cancer cell spheroids using Huh7 hepatocellular carcinoma (HCC) cells. The large Huh7 spheroids showed apoptotic and proliferative...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Jung, Hong-Ryul, Kang, Hyun Mi, Ryu, Jea-Woon, Kim, Dae-Soo, Noh, Kyung Hee, Kim, Eun-Su, Lee, Ho-Joon, Chung, Kyung-Sook, Cho, Hyun-Soo, Kim, Nam-Soon, Im, Dong-Soo, Lim, Jung Hwa, Jung, Cho-Rok
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585316/
https://ncbi.nlm.nih.gov/pubmed/28874716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10828-7
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