Plant-expressed cocaine hydrolase variants of butyrylcholinesterase exhibit altered allosteric effects of cholinesterase activity and increased inhibitor sensitivity

Butyrylcholinesterase (BChE) is an enzyme with broad substrate and ligand specificities and may function as a generalized bioscavenger by binding and/or hydrolyzing various xenobiotic agents and toxicants, many of which target the central and peripheral nervous systems. Variants of BChE were rationa...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Larrimore, Katherine E., Kazan, I. Can, Kannan, Latha, Kendle, R. Player, Jamal, Tameem, Barcus, Matthew, Bolia, Ashini, Brimijoin, Stephen, Zhan, Chang-Guo, Ozkan, S. Banu, Mor, Tsafrir S.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585256/
https://ncbi.nlm.nih.gov/pubmed/28874829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10571-z
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars