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Zinc depletion promotes apoptosis-like death in drug-sensitive and antimony-resistance Leishmania donovani

Micronutrients are essential for survival and growth for all the organisms including pathogens. In this manuscript, we report that zinc (Zn) chelator N,N,N’,N’-tetrakis(2-pyridinylmethyl)-1,2-ethylenediamine (TPEN) affects growth and viability of intracellular pathogen Leishmania donovani (LD) by a...

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Publicado en:Sci Rep
Main Authors: Saini, Shalini, Bharati, Kavita, Shaha, Chandrima, Mukhopadhyay, Chinmay K.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585245/
https://ncbi.nlm.nih.gov/pubmed/28874760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10041-6
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