Cell based assay identifies TLR2 and TLR4 stimulating impurities in Interferon beta

Immunogenicity can have devastating consequences on the safety and efficacy of therapeutic proteins. Therefore, evaluating and mitigating the risk of product immunogenicity is critical for the development these products. This study, showed that Betaseron and Extavia, which are reported to be more im...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Haile, Lydia Asrat, Polumuri, Swamy Kumar, Rao, Roshni, Kelley-Baker, Logan, Kryndushkin, Dimitri, Rajaiah, Rajesh, Israely, Tomer, Rao, V. Ashutosh, Verthelyi, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585229/
https://ncbi.nlm.nih.gov/pubmed/28874687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09981-w
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados