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Detection of Innate Immune Response Modulating Impurities in Therapeutic Proteins
Therapeutic proteins can contain multiple impurities, some of which are variants of the product, while others are derived from the cell substrate and the manufacturing process. Such impurities, even when present at trace levels, have the potential to activate innate immune cells in peripheral blood...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4406594/ https://ncbi.nlm.nih.gov/pubmed/25901912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125078 |
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