RIPK3/Fas-Associated Death Domain Axis Regulates Pulmonary Immunopathology to Cryptococcal Infection Independent of Necroptosis

Fas-associated death domain (FADD) and receptor interacting protein kinase 3 (RIPK3) are multifunctional regulators of cell death and immune response. Using a mouse model of cryptococcal infection, the roles of FADD and RIPK3 in anti-cryptococcal defense were investigated. Deletion of RIPK3 alone le...

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Publicat a:Front Immunol
Autors principals: Fa, Zhenzong, Xie, Qun, Fang, Wei, Zhang, Haibing, Zhang, Haiwei, Xu, Jintao, Pan, Weihua, Xu, Jinhua, Olszewski, Michal A., Deng, Xiaoming, Liao, Wanqing
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585137/
https://ncbi.nlm.nih.gov/pubmed/28919893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01055
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