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Inhibition of Endocannabinoid Metabolizing Enzymes in Peripheral Tissues Following Developmental Chlorpyrifos Exposure in Rats
Repeated developmental exposure to the organophosphate insecticide chlorpyrifos (CPF) inhibits brain fatty acid hydrolase (FAAH) activity at low levels, whereas at higher levels, it inhibits brain monoacylglycerol lipase (MAGL) activity. FAAH and MAGL hydrolyze the endocannabinoids anandamide (AEA)...
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| Publicado no: | Int J Toxicol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5585048/ https://ncbi.nlm.nih.gov/pubmed/28820005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1091581817725272 |
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