Decreased Anxiety in Juvenile Rats Following Exposure to Low Levels of Chlorpyrifos During Development

Exposure to chlorpyrifos (CPF) during the late preweanling period in rats inhibits the endocannabinoid metabolizing enzymes fatty acid hydrolase (FAAH) and monoacylglycerol lipase (MAGL), resulting in accumulation of their respective substrates anandamide (AEA) and 2-arachidonylglycerol (2-AG). This...

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Publicado no:Neurotoxicology
Main Authors: Carr, Russell L., Armstrong, Nathan H., Buchanan, Alenda T., Eells, Jeffrey B., Mohammed, Afzaal N., Ross, Matthew K., Nail, Carole A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580823/
https://ncbi.nlm.nih.gov/pubmed/26642910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2015.11.016
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