Bromide supplementation exacerbated the renal dysfunction, injury and fibrosis in a mouse model of Alport syndrome

A seminal study recently demonstrated that bromide (Br(-)) has a critical function in the assembly of type IV collagen in basement membrane (BM), and suggested that Br(-) supplementation has therapeutic potential for BM diseases. Because salts of bromide (KBr and NaBr) have been used as antiepilepti...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yokota, Tsubasa, Omachi, Kohei, Suico, Mary Ann, Kojima, Haruka, Kamura, Misato, Teramoto, Keisuke, Kaseda, Shota, Kuwazuru, Jun, Shuto, Tsuyoshi, Kai, Hirofumi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584969/
https://ncbi.nlm.nih.gov/pubmed/28873450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183959
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