Dual specificity phosphatase 6 deficiency is associated with impaired systemic glucose tolerance and reversible weight retardation in mice

Here, we aimed to investigate the potential role of DUSP6, a dual specificity phosphatase, that specifically inactivates extracellular signal-regulated kinase (ERK), for the regulation of body weight and glucose homeostasis. We further assessed whether metabolic challenges affect Dusp6 expression in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Pfuhlmann, Katrin, Pfluger, Paul T., Schriever, Sonja C., Müller, Timo D., Tschöp, Matthias H., Stemmer, Kerstin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584967/
https://ncbi.nlm.nih.gov/pubmed/28873424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183488
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