Perfluorocarbon emulsions radiosensitise brain tumors in carbogen breathing mice with orthotopic GL261 gliomas

BACKGROUND: Tumour hypoxia limits the effectiveness of radiation therapy. Delivering normobaric or hyperbaric oxygen therapy elevates pO(2) in both tumour and normal brain tissue. However, pO2 levels return to baseline within 15 minutes of stopping therapy. AIM: To investigate the effect of perfluor...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Feldman, Lisa A., Fabre, Marie-Sophie, Grasso, Carole, Reid, Dana, Broaddus, William C., Lanza, Gregory M., Spiess, Bruce D., Garbow, Joel R., McConnell, Melanie J., Herst, Patries M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584944/
https://ncbi.nlm.nih.gov/pubmed/28873460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184250
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