TGF-β signaling is an effective target to impair survival and induce apoptosis of human cholangiocarcinoma cells: A study on human primary cell cultures

Cholangiocarcinoma (CCA) and its subtypes (mucin- and mixed-CCA) arise from the neoplastic transformation of cholangiocytes, the epithelial cells lining the biliary tree. CCA has a high mortality rate owing to its aggressiveness, late diagnosis and high resistance to radiotherapy and chemotherapeuti...

Full description

Saved in:
Bibliographic Details
Published in:PLoS One
Main Authors: Lustri, Anna Maria, Di Matteo, Sabina, Fraveto, Alice, Costantini, Daniele, Cantafora, Alfredo, Napoletano, Chiara, Bragazzi, Maria Consiglia, Giuliante, Felice, De Rose, Agostino M., Berloco, Pasquale B., Grazi, Gian Luca, Carpino, Guido, Alvaro, Domenico
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584931/
https://ncbi.nlm.nih.gov/pubmed/28873435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183932
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items