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A fully humanized IgG-like bispecific antibody for effective dual targeting of CXCR3 and CCR6

Chemokines and their receptors are pivotal for the trafficking of leukocytes during immune responses, and host defense. However, immune cell migration also contributes to a wide variety of autoimmune and chronic inflammatory diseases. Compelling evidence suggests that both CXCR3 and CCR6 chemokine r...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Robert, Remy, Juglair, Laurent, Lim, Ee X., Ang, Caroline, Wang, Carl J. H., Ebert, Gregor, Dolezal, Olan, Mackay, Charles R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584921/
https://ncbi.nlm.nih.gov/pubmed/28873441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184278
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