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Essential role for CCR6 in certain inflammatory diseases demonstrated using specific antagonist and knockin mice
The chemokine receptor CCR6 marks subsets of T cells and innate lymphoid cells that produce IL-17 and IL-22, and as such may play a role in the recruitment of these cells to certain inflammatory sites. However, the precise role of CCR6 has been controversial, in part because no effective monoclonal...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5543919/ https://ncbi.nlm.nih.gov/pubmed/28768901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.94821 |
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