Chemokine receptor usage by human eosinophils. The importance of CCR3 demonstrated using an antagonistic monoclonal antibody.

Chemokines bind and signal through G-protein coupled seven transmembrane receptors. Various chemokine receptors are expressed on leukocytes, and these may impart selective homing of leukocyte subsets to sites of inflammation. Human eosinophils express the eotaxin receptor, CCR3, but respond to a var...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Heath, H, Qin, S, Rao, P, Wu, L, LaRosa, G, Kassam, N, Ponath, P D, Mackay, C R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507784/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9005985/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119145
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