A fully humanized IgG-like bispecific antibody for effective dual targeting of CXCR3 and CCR6

Chemokines and their receptors are pivotal for the trafficking of leukocytes during immune responses, and host defense. However, immune cell migration also contributes to a wide variety of autoimmune and chronic inflammatory diseases. Compelling evidence suggests that both CXCR3 and CCR6 chemokine r...

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Publicado en:PLoS One
Autores principales: Robert, Remy, Juglair, Laurent, Lim, Ee X., Ang, Caroline, Wang, Carl J. H., Ebert, Gregor, Dolezal, Olan, Mackay, Charles R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584921/
https://ncbi.nlm.nih.gov/pubmed/28873441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184278
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