Rational design of drug-like compounds targeting Mycobacterium marinum MelF protein

The mycobacterial mel2 locus (mycobacterial enhanced infection locus, Rv1936-1941) is Mycobacterium marinum and M. tuberculosis specific, which can withstand reactive oxygen species (ROS) and reactive nitrogen species (RNS) induced stress. A library of over a million compounds was screened using in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dharra, Renu, Talwar, Sakshi, Singh, Yogesh, Gupta, Rani, Cirillo, Jeffrey D., Pandey, Amit K., Kulharia, Mahesh, Mehta, Promod K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584760/
https://ncbi.nlm.nih.gov/pubmed/28873466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183060
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