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A Mycobacterium marinum mel2 Mutant Is Defective for Growth in Macrophages That Produce Reactive Oxygen and Reactive Nitrogen Species

Macrophages produce reactive oxygen species (ROS) and reactive nitrogen species (RNS) in response to bacterial infections. Mycobacteria are relatively resistant to ROS, but RNS inhibit growth of, and possibly even kill, mycobacteria in activated macrophages. We recently constructed a Mycobacterium m...

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Detalhes bibliográficos
Main Authors: Subbian, Selvakumar, Mehta, Parmod K., Cirillo, Suat L. G., Bermudez, Luiz E., Cirillo, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828420/
https://ncbi.nlm.nih.gov/pubmed/17030568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01000-06
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