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Duvelisib: A Phosphoinositide-3 Kinase δ/γ Inhibitor for Chronic Lymphocytic Leukemia

INTRODUCTION: Frontline chemotherapy is successful against chronic lymphocytic leukemia (CLL), but results in untoward toxicity. Further, prognostic factors, cytogenetic anomalies, and compensatory cellular signaling lead to therapy resistance or disease relapse. Therefore, for the past few years, d...

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Bibliographic Details
Published in:Expert Opin Investig Drugs
Main Authors: Vangapandu, Hima V., Jain, Nitin, Gandhi, Varsha
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584596/
https://ncbi.nlm.nih.gov/pubmed/28388280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13543784.2017.1312338
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