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Duvelisib: A Phosphoinositide-3 Kinase δ/γ Inhibitor for Chronic Lymphocytic Leukemia

INTRODUCTION: Frontline chemotherapy is successful against chronic lymphocytic leukemia (CLL), but results in untoward toxicity. Further, prognostic factors, cytogenetic anomalies, and compensatory cellular signaling lead to therapy resistance or disease relapse. Therefore, for the past few years, d...

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Detalhes bibliográficos
Publicado no:Expert Opin Investig Drugs
Main Authors: Vangapandu, Hima V., Jain, Nitin, Gandhi, Varsha
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584596/
https://ncbi.nlm.nih.gov/pubmed/28388280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13543784.2017.1312338
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