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Neuron-derived CCL2 contributes to microglia activation and neurological decline in hepatic encephalopathy

BACKGROUND: CCL2 was up-regulated in neurons and involved in microglia activation and neurological decline in mice suffering from hepatic encephalopathy (HE). However, no data exist concerning the effect of neuron-derived CCL2 on microglia activation in vitro. METHODS: The rats were pretreated with...

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Detalhes bibliográficos
Publicado no:Biol Res
Main Authors: Zhang, Li, Tan, Jinyun, Jiang, Xiaoping, Qian, Weiwei, Yang, Ting, Sun, Xijun, Chen, Zhaohui, Zhu, Qiwen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584513/
https://ncbi.nlm.nih.gov/pubmed/28870240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40659-017-0130-y
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