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Solution structure of an oligonucleotide containing an abasic site: evidence for an unusual deoxyribose conformation

The antitumor antibiotic bleomycin causes two major lesions in the deoxyribose backbone of DNA: formation of 4′-keto abasic sites and formation of strand breaks with 3′-phosphoglycolate and 5′-phosphate ends. As a model for the 4′-keto abasic site, we have characterized an abasic site (X) in d(CCAAA...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hoehn, Silvia T., Turner, Christopher J., Stubbe, JoAnne
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2001
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC55844/
https://ncbi.nlm.nih.gov/pubmed/11504879
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