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Comprehensive analyses of somatic TP53 mutation in tumors with variable mutant allele frequency
Somatic mutation of the tumor suppressor gene TP53 is reported in at least 50% of human malignancies. Most high-grade serous ovarian cancers (HGSC) have a mutant TP53 allele. Accurate detection of these mutants in heterogeneous tumor tissue is paramount as therapies emerge to target mutant p53. We u...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Sci Data |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5584393/ https://ncbi.nlm.nih.gov/pubmed/28872635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sdata.2017.120 |
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