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The oxido-metabolic driver ATF4 enhances temozolamide chemo-resistance in human gliomas
Malignant gliomas are devastating neoplasia with limited curative treatment options. Temozolomide (TMZ, Temcat(®), Temodal(®) or Temodar(®)) is a first-line treatment for malignant gliomas but the development of drug resistance remains a major concern. Activating transcription factor 4 (ATF4) is a c...
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| Publicado en: | Oncotarget |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5584239/ https://ncbi.nlm.nih.gov/pubmed/28881638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17737 |
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