Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema

The glutamate transporter xCT (SCL7a11, system Xc-, SXC) is an emerging key player in glutamate/cysteine/glutathione homeostasis in the brain and in cancer. xCT expression correlates with the grade of malignancy. Here, we report on the use of the U.S. Food and Drug Administration and EMA-approved xC...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Sehm, Tina, Fan, Zheng, Ghoochani, Ali, Rauh, Manfred, Engelhorn, Tobias, Minakaki, Georgia, Dörfler, Arnd, Klucken, Jochen, Buchfelder, Michael, Eyüpoglu, Ilker Y., Savaskan, Nicolai
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2016
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094980/
https://ncbi.nlm.nih.gov/pubmed/27074570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8651
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