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Sunitinib impedes brain tumor progression and reduces tumor-induced neurodegeneration in the microenvironment

Malignant gliomas can be counted to the most devastating tumors in humans. Novel therapies do not achieve significant prolonged survival rates. The cancer cells have an impact on the surrounding vital tissue and form tumor zones, which make up the tumor microenvironment. We investigated the effects...

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Dettagli Bibliografici
Pubblicato in:Cancer Sci
Autori principali: Hatipoglu, Gökçe, Hock, Stefan W, Weiss, Ruth, Fan, Zheng, Sehm, Tina, Ghoochani, Ali, Buchfelder, Michael, Savaskan, Nicolai E, Eyüpoglu, Ilker Y
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399021/
https://ncbi.nlm.nih.gov/pubmed/25458015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12580
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