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Sunitinib impedes brain tumor progression and reduces tumor-induced neurodegeneration in the microenvironment

Malignant gliomas can be counted to the most devastating tumors in humans. Novel therapies do not achieve significant prolonged survival rates. The cancer cells have an impact on the surrounding vital tissue and form tumor zones, which make up the tumor microenvironment. We investigated the effects...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Sci
Hauptverfasser: Hatipoglu, Gökçe, Hock, Stefan W, Weiss, Ruth, Fan, Zheng, Sehm, Tina, Ghoochani, Ali, Buchfelder, Michael, Savaskan, Nicolai E, Eyüpoglu, Ilker Y
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399021/
https://ncbi.nlm.nih.gov/pubmed/25458015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12580
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