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Dynamics of in vivo ASC speck formation
Activated danger or pathogen sensors trigger assembly of the inflammasome adaptor ASC into specks, large signaling platforms considered hallmarks of inflammasome activation. Because a lack of in vivo tools has prevented the study of endogenous ASC dynamics, we generated a live ASC reporter through C...
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| Publicado en: | J Cell Biol |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Rockefeller University Press
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5584180/ https://ncbi.nlm.nih.gov/pubmed/28701426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201703103 |
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