Mice overexpressing growth hormone exhibit increased skeletal muscle myostatin and MuRF1 with attenuation of muscle mass

BACKGROUND: In contrast to the acute effects of growth hormone (GH) on skeletal muscle protein synthesis, long-term GH treatment appears to have negligible effects on muscle mass. Despite this knowledge, little is known regarding the chronic effects of GH on skeletal muscle protein synthesis and atr...

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Veröffentlicht in:Skelet Muscle
Hauptverfasser: Consitt, Leslie A., Saneda, Alicson, Saxena, Gunjan, List, Edward O., Kopchick, John J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583757/
https://ncbi.nlm.nih.gov/pubmed/28870245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-017-0133-y
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