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Protein clustering for cell polarity: Par-3 as a paradigm

The scaffold protein Par-3 ( Drosophila Bazooka) is a central organizer of cell polarity across animals. This review focuses on how the clustering of Par-3 contributes to cell polarity. It begins with the Par-3 homo-oligomerization mechanism and its regulation by Par-1 phosphorylation. The role of p...

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Bibliografiske detaljer
Udgivet i:F1000Res
Hovedforfatter: Harris, Tony J. C.
Format: Artigo
Sprog:Inglês
Udgivet: F1000Research 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583741/
https://ncbi.nlm.nih.gov/pubmed/29026528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.11976.1
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