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Displacement of basolateral Bazooka/PAR-3 by regulated transport and dispersion during epithelial polarization in Drosophila

Polarity landmarks guide epithelial development. In the early Drosophila ectoderm, the scaffold protein Bazooka (Drosophila PAR-3) forms apicolateral landmarks to direct adherens junction assembly. However, it is unclear how Bazooka becomes polarized. We report two mechanisms acting in concert to di...

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Hlavní autoři: McKinley, R. F. Andrew, Harris, Tony J. C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496619/
https://ncbi.nlm.nih.gov/pubmed/23015757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-09-0655
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