Structural and Mechanistic Insights into the Improvement of the Halotolerance of a Marine Microbial Esterase by Increasing Intra- and Interdomain Hydrophobic Interactions

Halotolerant enzymes are beneficial for industrial processes requiring high salt concentrations and low water activity. Most halophilic proteins are evolved to have reduced hydrophobic interactions on the surface and in the hydrophobic cores for their haloadaptation. However, in this study, we impro...

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Dettagli Bibliografici
Pubblicato in:Appl Environ Microbiol
Autori principali: Li, Ping-Yi, Zhang, Yi, Xie, Bin-Bin, Zhang, Yan-Qi, Hao, Jie, Wang, Yue, Wang, Peng, Li, Chun-Yang, Qin, Qi-Long, Zhang, Xi-Ying, Su, Hai-Nan, Shi, Mei, Zhang, Yu-Zhong, Chen, Xiu-Lan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Enzymology and Protein Engineering
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583480/
https://ncbi.nlm.nih.gov/pubmed/28733281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01286-17
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