Interdomain Hydrophobic Interactions Modulate the Thermostability of Microbial Esterases from the Hormone-Sensitive Lipase Family

Microbial hormone-sensitive lipases (HSLs) contain a CAP domain and a catalytic domain. However, it remains unclear how the CAP domain interacts with the catalytic domain to maintain the stability of microbial HSLs. Here, we isolated an HSL esterase, E40, from a marine sedimental metagenomic library...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Li, Ping-Yi, Chen, Xiu-Lan, Ji, Peng, Li, Chun-Yang, Wang, Peng, Zhang, Yi, Xie, Bin-Bin, Qin, Qi-Long, Su, Hai-Nan, Zhou, Bai-Cheng, Zhang, Yu-Zhong, Zhang, Xi-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409275/
https://ncbi.nlm.nih.gov/pubmed/25771540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.646182
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