Targeting transferrin receptors at the blood-brain barrier improves the uptake of immunoliposomes and subsequent cargo transport into the brain parenchyma

Drug delivery to the brain is hampered by the presence of the blood-brain barrier, which excludes most molecules from freely diffusing into the brain, and tightly regulates the active transport mechanisms that ensure sufficient delivery of nutrients to the brain parenchyma. Harnessing the possibilit...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Johnsen, Kasper Bendix, Burkhart, Annette, Melander, Fredrik, Kempen, Paul Joseph, Vejlebo, Jonas Bruun, Siupka, Piotr, Nielsen, Morten Schallburg, Andresen, Thomas Lars, Moos, Torben
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583399/
https://ncbi.nlm.nih.gov/pubmed/28871203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11220-1
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge